A  -  B  =  C
            *
D  :  E  =  F
            =
G  +  H  =  I


Solution:
First of all no variable can be zero.
Therewise two variables would be equal.
The key are the two multiplications.

 C  *  F  =  I
 E  *  F  =  D

As only two products 2*3 and 2*4 are smaller than 10 
we get the two cases:
 F = 2, C = 3, E = 4  and 
 F = 2, C = 4, E = 3.
The rest is easily filled in.
The second case gives the unique solution

9  -  5  =  4
            *
6  :  3  =  2
            =
1  +  7  =  8